News & Research

arXiv:2512.08508v2 Announce Type: replace-cross Abstract: Identifying enzymes that catalyze target biochemical reactions is a key step in computational enzyme discovery and biocatalyst design. Recent representation-learning methods formulate this problem as enzyme--reaction matching, where paired enzymes and reactions are embedded into a shared space. However, most existing approaches primarily rely on pairwise enzyme--reaction supervision and make limited use of the relationships within reaction sets or enzyme families. This work introduces a multi-alignment contrastive learning framework for biochemical retrieval. The framework jointly models cross-domain compatibility between enzymes and reactions and within-domain relationships induced by functional annotations. In addition, a Gromov--Wasserstein-inspired regularization objective encourages geometric consistency between the learned enzyme and reaction representation spaces. By combining pairwise catalytic supervision with higher-or

arXiv:2512.08974v2 Announce Type: replace-cross Abstract: Severe convection produces localized hazards that often require warnings before radar echoes fully reveal storm development. Convective initiation and the maintenance of intense convection remain challenging for radar-only nowcasting because pre-convective signals may be absent from recent radar observations and strong echoes often decay rapidly in forecasts. Here we present FuXi-Nowcast, an environment-conditioned deep learning system that combines high-resolution observations with three-dimensional atmospheric forecasts to predict composite reflectivity, precipitation, wind gusts, and surface variables up to 12 h ahead. In April--July 2024 evaluations over East China, FuXi-Nowcast outperforms operational numerical, persistence and extrapolation baselines for reflectivity and precipitation. Case studies, diagnostics, and ablation experiments suggest that atmospheric moisture information and explicit preservation of strong conve

arXiv:2512.10506v3 Announce Type: replace-cross Abstract: Endmember extraction from hyperspectral images aims to identify the spectral signatures of materials present in a scene. Recent studies have shown that self-dictionary methods can achieve high extraction accuracy; however, their high computational cost limits their applicability to large-scale hyperspectral images. Although several approaches have been proposed to mitigate this issue, it remains a major challenge. Motivated by this situation, this paper pursues a data reduction approach. Assuming that a hyperspectral image follows the linear mixing model with the pure-pixel assumption, we develop a data reduction technique to remove pixels corresponding to mixtures of multiple endmember signatures. We analyze the theoretical properties of this reduction step and show that it preserves pixels that lie close to the endmembers. Building on this result, we propose a data-reduced self-dictionary method that integrates the data reduct

arXiv:2512.21815v3 Announce Type: replace-cross Abstract: Vision-language models (VLMs) achieve remarkable performance but remain vulnerable to adversarial attacks. Entropy, as a measure of model uncertainty, is highly correlated with VLM reliability. While prior entropy-based attacks maximize uncertainty at all decoding steps, implicitly assuming that every token equally contributes to model instability, we reveal that a small fraction (around 20%) of high-entropy tokens, in the evaluated representative open-source VLMs with diverse architectures, concentrates a disproportionate share of adversarial influence during autoregressive generation. We demonstrate that concentrating adversarial perturbations on these high-entropy positions achieves comparable semantic degradation to global methods while optimizing fewer decoding positions. Additionally, across multiple representative VLMs, such attacks induce not only semantic drift but also a substantial unsafe subset (20-31%) under the cur

arXiv:2512.23956v2 Announce Type: replace-cross Abstract: Flow Matching (FM) has emerged as a powerful paradigm for continuous normalizing flows, yet standard FM implicitly performs an unweighted $L^2$ regression over the entire ambient space. In high dimensions, this leads to a fundamental inefficiency: the vast majority of the integration domain consists of low-density ``void'' regions where the target velocity fields are often chaotic or ill-defined. In this paper, we propose {$\gamma$-Flow Matching ($\gamma$-FM)}, a density-weighted variant that aligns the regression geometry with the underlying probability flow. While density weighting is desirable, naive implementations would require evaluating the intractable target density. We circumvent this by introducing a Dynamic Density-Weighting strategy that estimates the \emph{target} density directly from training particles. This approach allows us to dynamically downweight the regression loss in void regions without compromising the s

arXiv:2512.23995v2 Announce Type: replace-cross Abstract: Mixture-of-Experts architectures have become the standard for scaling large language models due to their superior parameter efficiency. To accommodate the growing number of experts in practice, modern inference systems commonly adopt expert parallelism to distribute experts across devices. However, the absence of explicit load balancing constraints during inference allows adversarial inputs to trigger severe routing concentration. We demonstrate that out-of-distribution prompts can manipulate the routing strategy such that all tokens are consistently routed to the same set of top-$k$ experts, which creates computational bottlenecks on certain devices while forcing others to idle. This converts an efficiency mechanism into a denial-of-service attack vector, leading to violations of service-level agreements for time to first token. We propose RepetitionCurse, a low-cost black-box strategy to exploit this vulnerability. By identify

arXiv:2601.05289v2 Announce Type: replace-cross Abstract: The high-dimensional complex nature of detectors makes fast calorimeter simulations a prime application for modern generative machine learning. Vision transformers (ViTs) can emulate the Geant4 response with unmatched accuracy and are not limited to regular geometries. Starting from the CaloDREAM architecture, we demonstrate the robustness and scalability of ViTs on regular and irregular geometries, and multiple detectors. Our results show that ViTs generate electromagnetic and hadronic showers with minimal deviations from Geant4 in multiple evaluation metrics, while maintaining the generation time in the $\mathcal{O}(10-100)$ ms on a single GPU. Furthermore, we show that pretraining on a large dataset and fine-tuning on the target geometry leads to reduced training costs and higher data efficiency, or altogether improves the fidelity of generated showers.

arXiv:2601.07326v3 Announce Type: replace-cross Abstract: This paper studies the AdamW-style Shampoo optimizer, an effective implementation of classical Shampoo that notably won the external tuning track of the AlgoPerf neural network training algorithm competition. Our analysis unifies one-sided and two-sided preconditioning and establishes the convergence rate $\frac{1}{K}\sum_{k=1}^K E\left[\|\nabla f(X_k)\|_*\right]\leq O(\frac{\sqrt{m+n}C}{K^{1/4}})$ measured by nuclear norm, where $K$ represents the iteration number, $(m,n)$ denotes the size of matrix parameters, and $C$ matches the constant in the optimal convergence rate of SGD. Theoretically, we have $\|\nabla f(X)\|_F\leq \|\nabla f(X)\|_*\leq \sqrt{m+n}\|\nabla f(X)\|_F$, supporting that our convergence rate can be considered to be analogous to the optimal $\frac{1}{K}\sum_{k=1}^KE\left[\|\nabla f(X_k)\|_F\right]\leq O(\frac{C}{K^{1/4}})$ convergence rate of SGD in the ideal case of $\|\nabla f(X)\|_*= \Theta(\sqrt{m+n})\|\n

arXiv:2601.10494v2 Announce Type: replace-cross Abstract: With grid operators confronting rising uncertainty from renewable integration and a broader push toward electrification, Demand-Side Management (DSM) -- particularly Demand Response (DR) -- has attracted significant attention as a cost-effective mechanism for balancing modern electricity systems. Unprecedented volumes of consumption data from a continuing global deployment of smart meters enable consumer segmentation based on real usage behaviours, promising to inform the design of more effective DSM and DR programs. However, existing clustering-based segmentation methods insufficiently reflect the behavioural diversity of consumers, often relying on rigid temporal alignment, and faltering in the presence of anomalies, missing data, or large-scale deployments. To address these challenges, we propose a novel two-stage clustering framework -- Clustered Representations Optimising Consumer Segmentation (CROCS). In the first stage, e

arXiv:2601.14340v2 Announce Type: replace-cross Abstract: Large Language Models (LLMs) are widely integrated into interactive systems such as dialogue agents and task-oriented assistants. This growing ecosystem also raises supply-chain risks, where adversaries can distribute poisoned models that degrade downstream reliability and user trust. Existing backdoor attacks and defenses are largely prompt-centric, focusing on user-visible triggers while overlooking structural signals in multi-turn conversations. We propose Turn-based Structural Trigger (TST), a backdoor attack that activates from dialogue structure, using the turn index as the trigger and remaining independent of user inputs. This creates a structure-conditioned reliability risk: a backdoored model can pass prompt-centric checks and standard utility evaluations, yet execute attacker-specified behaviors at selected dialogue positions without any trigger in the user input. Across four open-source LLM families, TST achieves a 99

arXiv:2601.19743v3 Announce Type: replace-cross Abstract: Echocardiography is a cornerstone for managing heart failure (HF), with Left Ventricular Ejection Fraction (LVEF) being a critical metric for guiding therapy. However, manual LVEF assessment suffers from high inter-observer variability, while existing Deep Learning (DL) models are often computationally intensive and data-hungry "black boxes" that impede clinical trust and adoption. Here, we propose a backpropagation-free multi-task Green Learning (MTGL) framework that performs simultaneous Left Ventricle (LV) segmentation and LVEF classification. Our framework integrates an unsupervised VoxelHop encoder for hierarchical spatio-temporal feature extraction with a multi-level regression decoder and an XG-Boost classifier. On the EchoNet-Dynamic dataset, our MTGL model achieves state-of-the-art classification and segmentation performance, attaining a classification accuracy of 94.3% and a Dice Similarity Coefficient (DSC) of 0.912,

arXiv:2601.21406v3 Announce Type: replace-cross Abstract: Unified Multimodal Models (UMMs) integrate both visual understanding and generation within a single framework. Their ultimate aspiration is to create a cycle where understanding and generation mutually reinforce each other. While recent post-training methods have successfully leveraged understanding to enhance generation, the reverse direction of utilizing generation to improve understanding remains largely unexplored. In this work, we propose UniMRG (Unified Multi-Representation Generation), a simple yet effective architecture-agnostic post-training method. UniMRG enhances the understanding capabilities of UMMs by incorporating auxiliary generation tasks. Specifically, we train UMMs to generate multiple intrinsic representations of input images, namely pixel (reconstruction), depth (geometry), and segmentation (structure), alongside standard visual understanding objectives. By synthesizing these diverse representations, UMMs ca

arXiv:2601.21670v3 Announce Type: replace-cross Abstract: Multimodal fusion is often treated as an optimization-balancing problem, where training signals are adjusted to prevent one modality from dominating the others. However, balanced optimization does not fully determine the geometry of intermediate representations. Supervised multimodal models may still learn low-diversity modality-specific embeddings or allow paired cross-modal observations to drift excessively apart, weakening both unimodal robustness and multimodal fusion. We introduce \regName, a lightweight plug-and-play geometric regularization framework for multimodal representation learning. Rather than enforcing rigid cross-modal alignment, \regName follows a bounded-agreement principle: preserve modality-specific diversity while softly constraining only the portion of paired cross-modal drift that exceeds an admissible agreement band. Operationally, \regName combines a dispersion term that mitigates spectral concentration

arXiv:2602.01183v2 Announce Type: replace-cross Abstract: Biological learning proceeds from easy to difficult tasks, gradually reinforcing perception and robustness. Inspired by this principle, we address Context-Entangled Content Segmentation (CECS), a challenging setting where objects share intrinsic visual patterns with their surroundings, as in camouflaged object detection. Conventional segmentation networks predominantly rely on architectural enhancements but often ignore the learning dynamics that govern robustness under entangled data distributions. We introduce CurriSeg, a dual-phase learning framework that unifies curriculum and anti-curriculum principles to improve representation reliability. In the Curriculum Selection phase, CurriSeg dynamically selects training data based on the temporal statistics of sample losses, distinguishing hard-but-informative samples from noisy or ambiguous ones, thus enabling stable capability enhancement. In the Anti-Curriculum Promotion phase,

arXiv:2602.02979v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) have demonstrated strong potential in complex reasoning, yet their progress remains fundamentally constrained by reliance on massive high-quality human-curated tasks and labels, either through supervised fine-tuning (SFT) or reinforcement learning (RL) on reasoning-specific data. This dependence renders supervision-heavy training paradigms increasingly unsustainable, with signs of diminishing scalability already evident in practice. To overcome this limitation, we introduce CPM\"obius (CPMobius), a collaborative Coach-Player paradigm for data-free reinforcement learning of reasoning models. Unlike traditional adversarial self-play, CPM\"obius, inspired by real world human sports collaboration and multi-agent collaboration, treats the Coach and Player as independent but cooperative roles. The Coach proposes instructions targeted at the Player's capability and receives rewards based on changes in the P