Anatomy-Guided Vision-Language Learning with Angular Prototype Separation for Multi-Label Video Capsule Endoscopy Classification Under Class Imbalance
arXiv:2603.17879v2 Announce Type: replace Abstract: This work presents a multi-label temporal event detection framework for video capsule endoscopy (VCE) that addresses the extreme class imbalance inherent in the Galar dataset by combining two principal contributions: an Angular Separation Loss on class prototypes and a Biological State Machine temporal decoder. The backbone remains BiomedCLIP, a biomedical vision-language foundation model. Three consecutive frames are fused through a Local Differencing Attention module that amplifies transient pathological signals by suppressing static temporal redundancy. An Anatomy Context Head then conditions pathological predictions on soft anatomical activations, exploiting the known spatial co-occurrence structure of GI findings. Learnable text-feature prompts and prototype-based logit augmentation are trained alongside an Angular Separation Loss that penalizes off-diagonal cosine similarity between class prototypes, preventing the prototype col