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MetaboT: An LLM-based Multi-Agent Frameworkfor Interactive Analysis of Mass SpectrometryMetabolomics Knowledge Graphs

arXiv

arXiv:2510.01724v2 Announce Type: replace Abstract: Mass spectrometry-based metabolomics generates complex, high-dimensional data that holds vast potential for biological discovery but remains difficult to integrate and interpret. Knowledge graphs (KGs) unify this heterogeneous information by representing spectra, annotations, taxa, chemical classes, and biological activities as a single interoperable network; however, their practical use is limited by the steep learning curve of corresponding specialized representation and query languages. Here we introduce MetaboT, an open-source multi-agent Large Language Model (LLM) framework that translates natural-language questions into executable SPARQL queries over metabolomics knowledge graphs. MetaboT mitigates the hallucination and schema-compliance limitations of single-model approaches through a modular architecture in which specialised agents handle scope validation, entity resolution against authoritative resources, schema-aware query g

Bandwidth-Efficient and Privacy-Preserving Edge-Cloud Many-to-Many Speech Translation

arXiv

arXiv:2605.28642v1 Announce Type: new Abstract: Multimodal large language models (MLLMs) have demonstrated significant potential for speech-to-text translation (S2TT). However, existing deployment paradigms face critical challenges: pure on-device models suffer from resource constraints, while centralized cloud systems incur severe privacy risks and bandwidth bottlenecks by transmitting raw voice data. Furthermore, most models exhibit English-centric biases, restricting many-to-many translation scaling. In this paper, we propose Edge-cloud Speech Recognition and Translation (ESRT), a privacy-preserving and bandwidth-efficient collaborative edge-cloud MLLM framework. Specifically, we design an edge-cloud split inference architecture that retains a lightweight speech encoder and adapter on the device, transmitting only highly compressed intermediate features to the cloud. This fundamentally prevents voiceprint leakage and reduces bandwidth requirements by up to 10$\times$. To overcome En

GradientStabilizer:Fix the Norm, Not the Gradient

arXiv

arXiv:2502.17055v4 Announce Type: replace-cross Abstract: Training instability in modern deep learning systems is frequently triggered by rare but extreme gradient-norm spikes, which can induce oversized parameter updates, corrupt optimizer state, and lead to slow recovery or divergence. Widely used safeguards such as gradient clipping mitigate these failures but require threshold tuning and indiscriminately truncate large updates. We propose GradientStabilizer, a lightweight, drop-in gradient transform that preserves the instantaneous gradient direction while replacing the update magnitude with a statistically stabilized estimate derived from running gradient-norm statistics. We prove that the resulting stabilized magnitude is uniformly bounded on spike steps, independent of the spike size, and show how this boundedness controls optimizer state evolution in adaptive methods. Across LLM pre-training (FP16), quantization-aware pre-training (FP4), ImageNet classification, reinforcement l

control

Optimal and Diffusion Transports in Machine Learning

arXiv

arXiv:2512.06797v2 Announce Type: replace-cross Abstract: Several problems in machine learning are naturally expressed as the design and analysis of time-evolving probability distributions. This includes sampling via diffusion methods, optimizing the weights of neural networks, and analyzing the evolution of token distributions across layers of large language models. While the targeted applications differ (samples, weights, tokens), their mathematical descriptions share a common structure. A key idea is to switch from the Eulerian representation of densities to their Lagrangian counterpart through vector fields that advect particles. This dual view introduces challenges, notably the non-uniqueness of Lagrangian vector fields, but also opportunities to craft density evolutions and flows with favorable properties in terms of regularity, stability, and computational tractability. This survey presents an overview of these methods, with emphasis on two complementary approaches: diffusion me

Sequential Neural Probabilistic Amplitude Shaping: Learning the Channel's Language

arXiv

arXiv:2605.28143v1 Announce Type: new Abstract: We present the first neural probabilistic amplitude shaping that outperforms existing methods while accounting for all implementation losses, using a block-less, easily implementable sequential autoregressive encoder compatible with arithmetic distribution matching, yielding reduced rate loss and higher achievable information rates.

Revisiting Graph Autoencoders as Implicit Contrastive Learners

arXiv

arXiv:2410.10241v2 Announce Type: replace-cross Abstract: Graph autoencoders (GAEs) and graph contrastive learning (GCL) are two major paradigms for self-supervised representation learning on graphs, yet they are often studied in isolation and treated as fundamentally different approaches. In this work, we revisit GAEs through the lens of contrastive learning and show that both structure-based and feature-based GAEs can be conceptualized as implicitly graph contrastive learners. This perspective reveals that many existing GAEs differ primarily in how contrastive views are constructed, rather than in their learning objectives or architectures. Building on this insight, we introduce a unified formulation that highlights contrastive view design as a central and previously less explored dimension in GAEs. In particular, we identify asymmetric contrastive views, arising from mismatches in subgraph views, as an important yet underexplored design axis in prior GAE research. We formalize this

Sign-Aware Gated Sparse Autoencoders: Modeling Anticorrelated Features with Bi-Jump-ReLU Activations

arXiv

arXiv:2605.28149v1 Announce Type: new Abstract: Sparse Autoencoders (SAEs) extract interpretable features from Large Language Models, but standard variants enforce non-negativity, forcing separate latents for diametrically opposed concepts (e.g., "pressure too high" vs. "pressure too low") and wasting dictionary capacity when features are anticorrelated. We propose the Sign-Aware Gated SAE (SA-GSAE): two-sided gated sparsity with signed magnitude and auxiliary supervision. A polarity-sensitive gate selects support on either sign, a signed-magnitude path avoids L1 shrinkage, and an auxiliary reconstruction prevents gate collapse. Bipolar sharing - one latent encoding both signs along a shared direction - is realised via a new Bi-Jump-ReLU activation; parameter accounting shows sign-awareness stays parameter-efficient even when anticorrelated pairs are rare. On real LLM activations across three mid-depth hookpoints on Pythia-1B and SmolLM3-3B (6 cells, 3 seeds), a half-width SA-GSAE at w

hri

OphIn-500K: Curating Web-Scale Visual Instructions for Scaling Ophthalmic Multimodal Large Language Models

arXiv

arXiv:2605.27916v1 Announce Type: new Abstract: The advancement of general medical Multimodal Large Language Models (MLLMs) has shown great potential for building conversational assistants to support clinical diagnosis. However, their adaptation to highly specialized domains such as ophthalmology remains underexplored, primarily due to the scarcity of large-scale, domain-specific instruction-tuning data. Existing ophthalmic datasets for conversational agents are often limited in scale and largely rely on images from established public benchmarks, limiting the scalability of ophthalmic MLLMs and their ability to capture real-world clinical complexity. To address this gap, we propose $\textbf{OphIn-Engine}$, an ophthalmology-specific instruction data curation pipeline that constructs high-quality instruction data from open-access ophthalmology web-scale videos. The pipeline integrates multimodal transcription for extracting image-transcript pairs, visual cue separation and scoring for id

medical

OmniVerifier-M1: Multimodal Meta-Verifier with Explicit Structured Recalibration

arXiv

arXiv:2605.28805v1 Announce Type: cross Abstract: Visual outcomes are increasingly central to multimodal large language models, making reliable and fine-grained verification essential for scaling generalist foundation models. In this work, we investigate multimodal meta-verification, which leverages verifier-generated rationales rather than decision-only signals, and explore how to effectively incorporate meta-verification feedback into multimodal verifier training. We identify two key findings. First, symbolic verifier outputs (e.g., bounding boxes) outperform textual explanations as meta-verification rationales, enabling efficient rule-based reinforcement learning rewards while avoiding reliance on model-based rewards from auxiliary judge models. Second, decoupling reinforcement learning objectives for binary judgment and meta-verification substantially outperforms joint reward optimization, due to intrinsic differences in output structure and learning dynamics. Based on these insigh

reinforcement-learning

Auditable Decision Models with Learned Abstention and Real-Time Steering

arXiv

arXiv:2605.27768v1 Announce Type: new Abstract: Production AI systems often operate with incomplete, conflicting, or insufficient evidence. Forced classifiers collapse such cases into action labels, while generative systems can produce outputs that are difficult to interpret as auditable execution decisions. We study operational decision control for AI systems, where uncertainty must be explicitly routable, policy-governed, and auditable rather than hidden inside forced predictions or free-form generation. We present EvaluatorDPT, a bounded decision-control model that predicts YES, NO, or TBD, where TBD is learned as a deferral outcome rather than added only as a post-hoc confidence rule. The model uses a transformer encoder with a primary bounded-decision head and structured auxiliary channels for values and emotions/sentiments. The interface is domain-agnostic in form: a deployment domain supplies evidence and policy thresholds, while the model emits a bounded distribution that can b

control

Mind the Gap: Mixtures of Gaussians in Approximate Differential Privacy

arXiv

arXiv:2605.28078v1 Announce Type: cross Abstract: We design a class of additive noise mechanisms that satisfy \((\varepsilon, \delta)\)-differential privacy (DP) for scalar, real-valued query functions with known sensitivities, with a particular focus on moderate and low-privacy regimes. These mechanisms, which we call \textit{mixture mechanisms}, are constructed by mixing multiple Gaussian distributions that share the same variance but differ in their means and mixture weights. The resulting distributions can be interpreted as convex combinations of a zero-mean Gaussian (as used in the analytic Gaussian mechanism) and additional Gaussians whose means depend on the sensitivity of the query function. We derive tight conditions on the variances required for \((\varepsilon, \delta)\)-DP and provide efficient algorithms to compute them. Compared to the analytic Gaussian mechanism, our mechanisms yield substantially lower expected noise amplitudes (\(l_1\)-loss) and variances (\(l_2\)-loss

Event-based Motion & Appearance Fusion for 6D Object Pose Tracking

arXiv

arXiv:2603.08264v2 Announce Type: replace Abstract: Object pose tracking is a fundamental and essential task for robotics to perform tasks in the home and industrial settings. The most commonly used sensors to do so are RGB-D cameras, which can hit limitations in highly dynamic environments due to motion blur and frame-rate constraints. Event cameras have remarkable features such as high temporal resolution and low latency, which make them a potentially ideal vision sensors for object pose tracking at high speed. Even so, there are still only few works on 6D pose tracking with event cameras. In this work, we take advantage of the high temporal resolution and propose a method that uses both a propagation step fused with a pose correction strategy. Specifically, we use 6D object velocity obtained from event-based optical flow for pose propagation, after which, a template-based local pose correction module is utilized for pose correction. Our learning-free method has comparable performanc

VibeSearchBench: Benchmarking Long-horizon Proactive Search in the Wild

arXiv

arXiv:2605.27882v1 Announce Type: cross Abstract: LLM-based agents score well on search benchmarks, yet real users consistently find results unsatisfying, revealing a persistent evaluation-experience gap. We attribute this gap to existing benchmarks' reliance on over-specified queries, single-turn interactions, and fixed-schema evaluation, none of which reflect real search behavior where users and agents collaboratively refine vague intent through multi-turn dialogue. We term this paradigm VibeSearch and introduce VibeSearchBench, a benchmark comprising 200 manually curated bilingual (Chinese and English) tasks across 20 domains, split into VibeSearch-Pro (professional) and VibeSearch-Daily (daily-life) subsets. Each task pairs a user persona with a schema-free ground-truth knowledge graph, and is evaluated through a progressive-disclosure user simulator and a graph-matching evaluation framework. We benchmark seven frontier models under both the ReAct framework and the OpenClaw agent h

Semantic Optimal Transport for Sparse Autoencoder Feature Matching and Circuit Compression

arXiv

arXiv:2605.28567v1 Announce Type: cross Abstract: Sparse autoencoders (SAEs) have become a central tool for interpreting language models. However, two key SAE analyses that remain difficult to scale are (1) matching semantically similar features across multi-layers and (2) compressing large feature circuits into interpretable supernodes. Although these have been treated as separate problems, we show that both are instances of a more fundamental challenge, which we frame as the estimation of semantic distances between SAE features that lie on different activation manifolds. We introduce a distributional framework for this problem, in which each feature is represented not by a single decoder vector like in the literature, but by an activation-weighted distribution over the hidden states that express it. By projecting these distributions into a shared reference space and comparing them with Wasserstein distance, our method provides a unified semantic metric for cross-layer feature compari

Turning Video Models into Generalist Robot Policies

arXiv

arXiv:2605.27817v1 Announce Type: new Abstract: Video generative models have emerged as a promising robotics backbone, capable of generating videos that depict the completion of complex tasks across embodiments and environments. Recent work proposes robot foundation models that jointly predict future observations and actions by finetuning video models with action-labeled data. In this paper, we test the limits of an alternative approach: leave the video planner as-is while training an embodiment-specific inverse dynamics model (IDM). This decoupling offers several natural benefits: the video planner remains embodiment-agnostic, different video models can be interchanged easily without re-training the IDM, and the IDM can be independently trained with readily available self-play data. We present a closed-loop, video-to-action policy that combines an action-free video world model with a carefully-designed IDM based on the robot embodiment Jacobian. We demonstrate that our IDM design is b

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